Doctors are using pharmacogenomics to help determine what drugs will work, and which drugs to avoid.
not new, but more and more doctors are testing their patients to see how they process a variety of drugs from pain relievers to cardio medications. This will tell them who the medication will work for, who it won’t, and who might have a severe drug reaction and avoid that.
Doctors keep the genetic information on file so they can check to see if a drug will work or cause a problem before prescribing it. This helps take the guesswork out of prescriptions.
Pharmacogenomics not only helps with medications patients are currently taking, but will guide their future prescriptions and potentially save lives.
PGx Medical is the trusted and experienced resource for the implementation of pharmacogenetics into the field of aging services.
For more information, contact:
PGx Medical info@pgxmed.com
405-509-5112
Each Friday we will post new and relevant information regarding Pharmacogenetics. We hope you will find this useful and pass along to colleagues. If you should have any questions regarding pharmacogenetics, please feel free to reach out to us at PGx Medical, info@pgxmed.com or 405-509-5112.
One question we get asked a lot when we travel around the country educating healthcare professionals on pharmacogenetics is…
Who should be tested?
Even though our pharmacogenetic program is a once in a lifetime test and reimbursed by medicare and in some states medicaid…it isn’t for everyone.
If you have a resident at your LTC facility who isn’t taking any medications, there is no need to test that resident. The following are a few reasons why I resident would benefit from pharmacogenetic testing.
Taking multiple medications. You are having problems that you write-off as side effects from your medication. It may be that your drugs are interacting. How would you know without a pharmacogenetic test? Drug interactions may make your drug less effective, cause unexpected side effects, or increase the action of a particular drug. Some drug interactions can even be harmful to you. The PGx Medical test result highlights potential drug-on-drug reactions so healthcare professionals can dose accordingly.
You’ve been taking your medication but your condition is not improving. Have you ever heard the phrase, “let’s try it for a few weeks and see if you improve.” That is called trial and error and honestly, how physicians prescribed medicine because they didn’t know the genetic make-up of each patient. Now, pharmacogenetic testing can help guide healthcare professionals in proper prescribing by aligning medications with each person’s unique genetic profile. And the test report will show them more effective options.
Your physician has prescribed an anticoagulant. The FDA recommends individuals be aware of pharmacogenetics prior to starting certain anticoagulants such as Plavix and Warfarin. Patients who are poor metabolizers of these medications may be at risk – or may not be receiving the full benefit of these drugs.
Pharmacogenetics can help identify genetic markers and can assist in individualization of treatment.
PGx Medical is the trusted and experienced resource for the implementation of pharmacogenetics in the field of aging services. Contact us for more information, or let us know if you would like to be part of a Patient-Centered Care Pharmacogenetic Pilot Program. In conjunction with Dr. Linda Shell, PGx Medical is presently enrolling provider organizations and communities. To see if you qualify, go to: www.pgxmed.com/pilotprogram.
More and more patients are being screened to help cut out ineffective medicine and avoid harmful drug interactions
More patients are taking five or more prescription medications at once, putting them at risk for side effects and drug interactions. Amid concern about the potential harm of taking too many drugs, more doctors are deprescribing, getting patients off prescriptions that are no longer necessary.~WSJ
According to a recent article in the Wall Street Journal, nearly 40% of patients in their 60s take more than five medications.
“What was good for you once might not be as good for you now,” says Cara Tannenbaum, a geriatrician and the scientific director of the Institute of Gender and Health at the Canadian Institutes of Health Research in Montreal. “On a regular basis, patients should be asking their health-care providers, ‘Is this still the right drug for me, and if not, what other drug or nondrug therapies are safer and equally effective?’ ”
Dr. Tannenbaum and pharmacist Barbara Farrell have developed a website, deprescribing.org, which is maintained by the Canadian Deprescribing Network, a group that includes health professionals, policy makers and patient advocates. The site, used by doctors in both the U.S. and Canada, provides information to help patients determine if they should consider stopping certain medications that may be unnecessary or cause harm, including a common medication for heartburn or reflux called a proton pump inhibitor and certain diabetes drugs that increase the risk for low blood sugar.
Medication use can start to pile up in middle age or earlier, especially in patients being treated for diabetes, heart disease or cancer. People may see different doctors who don’t coordinate care with each other. Soon, they are in a situation known as polypharmacy, defined as five or more drugs.
The body processes many drugs less efficiently as it ages, leading to problems with long-term medications. Statins, prescribed to control cholesterol, may not be needed over age 75, and they can cause muscle weakness and increase the risk of falls.
The American Geriatrics Society last year updated its Beers Criteria, a list of 40 medications or classes of drugs that are potentially inappropriate for older adults. An expert panel is working on an update for 2018.
“The goal is to keep patients as healthy as possible on the least number of medications.”
Pharmacogenetics is a tool used by doctors across the country to provide evidence-based results on how a person metabolizes medications. This simple swab of the cheek is a guide to help clinicians with current medication regimen, as well as a roadmap for future medications.
“Knowing that a medication doesn’t have the ability to give a patient therapy is a great way to deprescribe. You have evidence that person is not receiving therapy because their body does not metabolize that particular drug the way the drug manufacturer intended you to – making it easier to deprescribe, or discontinue that medication,” said Clay Bullard, President of PGx Medical a pharmacogenetic consulting firm headquartered in Edmond, OK.
“We work within the field of aging services across the country educating them on the benefits and value pharmacogenetics brings to not only the patient, but the caregiver and the community when dealing with a nursing home or assisted living facility, Our job is to be experts in the field of pharmacogenetics and then educate and help implement the test in communities, clinics and pharmacies across the U.S.”
Pharmacogenetics is fully reimbursed by Medicare B and in select states, Medicaid. As stated in the WSJ article, by eliminating multiple drugs, you help reduce the chance of falls, drug interactions, and many other clinical concerns.
For more information about pharmacogenetic testing, contact:
PGx Medical
info@pgxmed.com or 405-509-5112
or go to www.pgxmed.com
